| 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage | Round of 16 |
| Quarterfinals | Semifinals | Final |
Round:
Played
1st Round
09/15/2021 - Wednesday
12:00
Atlético de Madrid
0
x
0
Porto
12:00
Liverpool
3
x
2
Milan
2nd Round
09/28/2021 - Tuesday
12:00
Milan
1
x
2
Atlético de Madrid
12:00
Porto
1
x
5
Liverpool
3rd Round
10/19/2021 - Tuesday
12:00
Atlético de Madrid
2
x
3
Liverpool
12:00
Porto
1
x
0
Milan
4th Round
11/03/2021 - Wednesday
10:45
Milan
1
x
1
Porto
13:00
Liverpool
2
x
0
Atlético de Madrid
5th Round
11/24/2021 - Wednesday
12:00
Atlético de Madrid
0
x
1
Milan
12:00
Liverpool
2
x
0
Porto
6th Round
12/07/2021 - Tuesday
12:00
Milan
1
x
2
Liverpool
12:00
Porto
1
x
3
Atlético de Madrid