| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas de Final | Quartas de Final |
| Semifinais | Final |
Round:
Played
1st Round
04/21/2021 - Wednesday
17:00
Independiente del Valle
1
x
1
Defensa y Justicia
17:00
Universitario
2
x
3
Palmeiras-SP
2nd Round
04/27/2021 - Tuesday
17:30
Palmeiras-SP
5
x
0
Independiente del Valle
04/28/2021 - Wednesday
15:00
Defensa y Justicia
3
x
0
Universitario
3rd Round
05/04/2021 - Tuesday
17:30
Defensa y Justicia
1
x
2
Palmeiras-SP
05/05/2021 - Wednesday
15:00
Independiente del Valle
4
x
0
Universitario
4th Round
05/11/2021 - Tuesday
17:30
Independiente del Valle
0
x
1
Palmeiras-SP
05/12/2021 - Wednesday
19:00
Universitario
1
x
1
Defensa y Justicia
5th Round
05/18/2021 - Tuesday
15:15
Palmeiras-SP
3
x
4
Defensa y Justicia
17:30
Universitario
3
x
2
Independiente del Valle
6th Round
05/27/2021 - Thursday
15:00
Defensa y Justicia
1
x
1
Independiente del Valle
15:00
Palmeiras-SP
6
x
0
Universitario