| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas de Final | Quartas de Final |
| Semifinal | Final |
Round:
Played
2nd Round
04/04/2018 - Wednesday
17:45
Boca Juniors
1
x
0
Junior Barranquilla
17:45
Cruzeiro-MG
0
x
0
Vasco-RJ
04/05/2018 - Thursday
15:15
River Plate
0
x
0
Santa Fe
3rd Round
04/05/2018 - Thursday
15:15
Colo-Colo
0
x
2
Delfín
17:30
Bolivar
1
x
0
Atlético Nacional
17:30
Estudiantes
0
x
1
Santos-SP
04/11/2018 - Wednesday
17:45
Palmeiras-SP
1
x
1
Boca Juniors
04/17/2018 - Tuesday
15:15
Defensor Sporting
3
x
1
Monagas
17:30
Cerro Porteño
0
x
0
Grêmio-RS
17:30
Millonarios
4
x
0
Deportivo Lara
04/18/2018 - Wednesday
15:15
The Strongest
1
x
2
Atlético Tucumán
17:45
Flamengo-RJ
1
x
1
Santa Fe
17:45
Independiente
0
x
1
Corinthians-SP
17:45
Libertad
2
x
1
Peñarol
04/19/2018 - Thursday
15:15
Racing Club
4
x
0
Vasco-RJ
17:30
Alianza Lima
0
x
2
Junior Barranquilla
17:30
Emelec
0
x
1
River Plate
17:30
Universidad de Chile
0
x
0
Cruzeiro-MG
4th Round
04/24/2018 - Tuesday
15:15
Deportivo Lara
2
x
1
Millonarios
17:30
Atlético Nacional
4
x
1
Bolivar
17:30
Santos-SP
2
x
0
Estudiantes
04/25/2018 - Wednesday
15:15
Atlético Tucumán
3
x
0
The Strongest
15:15
Nacional-URU
4
x
0
Cusco
17:45
Boca Juniors
0
x
2
Palmeiras-SP
17:45
Monagas
1
x
0
Defensor Sporting
17:45
Santa Fe
0
x
0
Flamengo-RJ
04/26/2018 - Thursday
15:15
Cruzeiro-MG
7
x
0
Universidad de Chile
15:15
River Plate
2
x
1
Emelec
17:30
Junior Barranquilla
1
x
0
Alianza Lima
17:30
Peñarol
2
x
0
Libertad